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UniProt B1MD46

Dihydrofolate reductase (B1MD46)

Dihydrofolate reductase (UniProt B1MD46), EC 1.5.1.3: 2 experimental structures on GenesisL1, 3 ligands bound, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
B1MD46
Protein
Dihydrofolate reductase
EC
1.5.1.3
Experimental structures
2
Predicted models
0
Ligands
3
Pockets
19 · 1 record with a druggable one

Structures

2 records of B1MD46 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7K6CCrystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium abscessus ATCC 19977 / DSM…x-ray diffractionA, B, C, D, E, F, GNAP, MMV, CA19 (best 0.74)
7K6CCrystal structure of dihydrofolate reductase (DHFR) from mycobacterium abscessus atcc 19977 / dsm…x-ray diffractionA, B, C, D, E, F, GNAP, MMV, CA—

Ligands

  • CA · Calcium ion · in 2 records
  • MMV · 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl) oxy]propoxy}phenyl)propanoic acid · in 2 records
  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · in 2 records

Elsewhere

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