UniProt A6ZMK5
Eukaryotic translation initiation factor 3 subunit I (A6ZMK5)
Eukaryotic translation initiation factor 3 subunit I (UniProt A6ZMK5): 4 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A6ZMK5
- Protein
- Eukaryotic translation initiation factor 3 subunit I
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 6 · 2 records with a druggable one
Structures
5 records of A6ZMK5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4U1E | Crystal structure of the eIF3b-CTD/eIF3i/eIF3g-NTD translation initiation complex | x-ray diffraction | I | — | 5 (best 0.81) |
| 4U1E | Crystal structure of the EIF3B-CTD/EIF3I/EIF3G-ntd translation initiation complex | x-ray diffraction | I | — | — |
| 6FYY | Structure of a partial yeast 48S preinitiation complex with eIF5 N-terminal domain (model C2) | electron microscopy | s | — | — |
| 6GSN | Structure of a partial yeast 48S preinitiation complex in closed conformation | electron microscopy | s | — | 1 (best 0.81) |
| A6ZMK5 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 3 subunit I (A6ZMK5) | predicted | A | — | — |
Experiment against prediction
- 4U1E chain I against the predicted model A6ZMK5: TM-score 0.99, RMSD 0.77 Å
- 4U1E chain I against the predicted model A6ZMK5: TM-score 0.99, RMSD 0.77 Å
- 6GSN chain s against the predicted model A6ZMK5: TM-score 0.99, RMSD 0.77 Å
- 6FYY chain s against the predicted model A6ZMK5: TM-score 0.99, RMSD 0.82 Å
Elsewhere
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