UniProt A6ND01
Sperm-egg fusion protein Juno (A6ND01)
Sperm-egg fusion protein Juno (UniProt A6ND01): 14 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A6ND01
- Protein
- Sperm-egg fusion protein Juno
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 14 · 3 records with a druggable one
Structures
15 records of A6ND01 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5F4E | Crystal structure of the human sperm Izumo1 and egg Juno complex | x-ray diffraction | B | CL | — |
| 5F4E | Crystal structure of the human sperm IZUMO1 and egg juno complex | x-ray diffraction | B | — | — |
| 5F4Q | Crystal structure of the human egg surface protein Juno | x-ray diffraction | A, B, C, D | NAG, CL | — |
| 5F4Q | Crystal structure of the human egg surface protein juno | x-ray diffraction | A, B, C, D | — | — |
| 5JKA | Crystal structure of human JUNO (crystal form 1) | x-ray diffraction | B, A | NAG, CL | — |
| 5JKA | Crystal structure of human juno (crystal form 1) | x-ray diffraction | B, A | — | — |
| 5JKB | Crystal structure of human JUNO (crystal form 2) | x-ray diffraction | A, B, C, D | CL | — |
| 5JKB | Crystal structure of human juno (crystal form 2) | x-ray diffraction | A, B, C, D | — | — |
| 5JKC | Crystal structure of human IZUMO1-JUNO complex (crystal form 1) | x-ray diffraction | B | NAG, CL | 3 (best 0.63) |
| 5JKC | Crystal structure of human IZUMO1-juno complex (crystal form 1) | x-ray diffraction | B | — | — |
| 5JKD | Crystal structure of human IZUMO1-JUNO complex (crystal form 2) | x-ray diffraction | B | NAG, CL | 3 (best 0.63) |
| 5JKD | Crystal structure of human IZUMO1-juno complex (crystal form 2) | x-ray diffraction | B | — | — |
| 5JKE | Crystal structure of human IZUMO1-JUNO complex (crystal form 3) | x-ray diffraction | B, D | NAG, CL, SO4 | 8 (best 0.65) |
| 5JKE | Crystal structure of human IZUMO1-juno complex (crystal form 3) | x-ray diffraction | B, D | — | — |
| A6ND01 | AlphaFold monomer V2.0 prediction for sperm-egg fusion protein juno (A6ND01) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5JKB chain C against the predicted model A6ND01: TM-score 0.97, RMSD 0.92 Å
- 5JKB chain C against the predicted model A6ND01: TM-score 0.97, RMSD 0.92 Å
- 5F4Q chain A against the predicted model A6ND01: TM-score 0.97, RMSD 0.99 Å
- 5F4Q chain A against the predicted model A6ND01: TM-score 0.97, RMSD 0.99 Å
- 5JKB chain A against the predicted model A6ND01: TM-score 0.97, RMSD 1.17 Å
- 5JKB chain A against the predicted model A6ND01: TM-score 0.97, RMSD 1.17 Å
- 5JKA chain B against the predicted model A6ND01: TM-score 0.97, RMSD 1.08 Å
- 5JKA chain B against the predicted model A6ND01: TM-score 0.97, RMSD 1.08 Å
- 5JKA chain A against the predicted model A6ND01: TM-score 0.96, RMSD 1.31 Å
- 5JKA chain A against the predicted model A6ND01: TM-score 0.96, RMSD 1.31 Å
Elsewhere
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