UniProt A3RL54
Sperm-specific sodium proton exchanger (A3RL54)
Sperm-specific sodium proton exchanger (UniProt A3RL54): 8 experimental structures on GenesisL1, 4 ligands bound, 141 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A3RL54
- Protein
- Sperm-specific sodium proton exchanger
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 141 · 8 records with a druggable one
Structures
8 records of A3RL54 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8OTQ | Cryo-EM structure of Strongylocentrotus purpuratus sperm-specific Na+/H+ exchanger SLC9C1 in GDN | electron microscopy | A, B | CPL, PLM | 20 (best 0.85) |
| 8OTX | Cryo-EM structure of Strongylocentrotus purpuratus sperm-specific Na+/H+ exchanger SLC9C1 in… | electron microscopy | B, A | 3PH | 20 (best 0.85) |
| 8PD3 | Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 2 | electron microscopy | A | — | 13 (best 0.76) |
| 8PD7 | Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 4 | electron microscopy | A | — | 19 (best 0.72) |
| 8PD8 | cAMP-bound SpSLC9C1 in lipid nanodiscs, dimer | electron microscopy | A, B | CMP | 20 (best 0.83) |
| 8XQ4 | Structure of the sea urchin spSLC9C1 in state-2 w/o cAMP protomer | electron microscopy | A | — | 16 (best 0.74) |
| 8XQ8 | Structure of the sea urchin spSLC9C1 in state-1 w/ cAMP protomer | electron microscopy | A | CMP | 13 (best 0.74) |
| 8XQ9 | Structure of the sea urchin spSLC9C1 in state-2 w/ cAMP dimer | electron microscopy | A, B | — | 20 (best 0.82) |
Ligands
Elsewhere
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