UniProt A1AGK6
50S ribosomal protein L4 (A1AGK6)
50S ribosomal protein L4 (UniProt A1AGK6): 33 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- A1AGK6
- Protein
- 50S ribosomal protein L4
- Experimental structures
- 33
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 36 · 29 records with a druggable one
Structures
34 records of A1AGK6 in the MolNFT archive: 33 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8EKC | Escherichia coli 70S ribosome bound to thermorubin, deacylated P-site tRNAfMet and aminoacylated… | electron microscopy | E | MG | 1 (best 0.86) |
| 8FZD | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with apoRF3, RF1, P… | electron microscopy | E | MG | 1 (best 0.86) |
| 8FZE | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and… | electron microscopy | E | MG | — |
| 8FZF | Cryo-EM structure of an E. coli rotated ribosome complex bound with RF3-ppGpp and p/E-tRNAPhe… | electron microscopy | E | MG | 1 (best 0.87) |
| 8FZG | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF3-GDPCP, RF1… | electron microscopy | E | MG | 1 (best 0.88) |
| 8FZH | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and… | electron microscopy | E | MG | — |
| 8FZI | Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite… | electron microscopy | E | MG | 2 (best 0.86) |
| 8FZJ | Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite… | electron microscopy | E | MG | 1 (best 0.87) |
| 8G38 | Time-resolved cryo-EM study of the 70S recycling by the HflX:3rd Intermediate | electron microscopy | E | — | — |
| 8G6W | Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site… | electron microscopy | e | MG | 1 (best 0.83) |
| 8G6Y | Structure of WT E.coli ribosome 50S subunit with complexed with mRNA, P-site fMet-NH-tRNAfMet and… | electron microscopy | e | MG | 2 (best 0.85) |
| 8G7P | Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to… | electron microscopy | E | MG | 1 (best 0.83) |
| 8G7Q | Structure of the Escherichia coli 70S ribosome in complex with EF-Tu and Ile-tRNAIle(LAU) bound to… | electron microscopy | E | MG | 1 (best 0.82) |
| 8G7R | Structure of the Escherichia coli 70S ribosome in complex with A-site tRNAIle(LAU) bound to the… | electron microscopy | E | MG | — |
| 8G7S | Structure of the Escherichia coli 70S ribosome in complex with P-site tRNAIle(LAU) bound to the… | electron microscopy | E | MG | 2 (best 0.85) |
| 8SYL | Cryo-EM structure of the Escherichia coli 70S ribosome in complex with amikacin, mRNA, and A-, P… | electron microscopy | E | MG | 1 (best 0.85) |
| 8T5D | Cryo-EM studies of the interplay between uS2 ribosomal protein and leaderless mRNA during bacterial… | electron microscopy | E | — | 3 (best 0.86) |
| 8T5H | Cryo-EM studies of the interplay between uS2 ribosomal protein and leaderless mRNA during bacterial… | electron microscopy | E | — | 1 (best 0.88) |
| 8UPO | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to… | electron microscopy | l | — | 1 (best 0.88) |
| 8UPR | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to… | electron microscopy | l | — | 2 (best 0.86) |
| 8UQM | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in… | electron microscopy | l | — | 1 (best 0.85) |
| 8UQP | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to… | electron microscopy | l | — | 1 (best 0.89) |
| 8UR0 | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to… | electron microscopy | l | — | 2 (best 0.88) |
| 8URH | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to… | electron microscopy | l | — | 1 (best 0.85) |
| 8URI | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to… | electron microscopy | l | — | 1 (best 0.86) |
| 8URX | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to… | electron microscopy | l | — | 1 (best 0.85) |
| 8VS9 | Endogenous trans-translation complex with tmRNA*SmpB in the P site and alanyl-tRNA in the A site… | electron microscopy | L04 | — | 1 (best 0.86) |
| 8VSA | Endogenous trans-translation complex with tmRNA*SmpB in the P site and alanyl-tRNA in the A site of… | electron microscopy | L04 | — | 1 (best 0.83) |
| 9AX7 | 70S initiation complex (tRNA-fMet M1 + CUG start codon) | electron microscopy | e | MG | 1 (best 0.85) |
| 9AX8 | 70S initiation complex (tRNA-fMet M1, initiation factor 2 + CUG start codon) | electron microscopy | E | MG | 1 (best 0.87) |
| 9CG5 | 70S initiation complex (tRNA-fMet M1 + UUG start codon) | electron microscopy | e | MG | 1 (best 0.86) |
| 9CG6 | 70S initiation complex (tRNA-fMet M1 + GUG start codon) | electron microscopy | e | MG | 1 (best 0.85) |
| 9CG7 | 70S initiation complex (tRNA-fMet M1 + AUG start codon) | electron microscopy | e | MG | 1 (best 0.85) |
| A1AGK6 | AlphaFold monomer V2.0 prediction for 50S ribosomal protein L4 (A1AGK6) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 20 records
Experiment against prediction
- 8SYL chain E against the predicted model A1AGK6: TM-score 0.97, RMSD 0.88 Å
- 9CG6 chain e against the predicted model A1AGK6: TM-score 0.97, RMSD 0.91 Å
- 9CG7 chain e against the predicted model A1AGK6: TM-score 0.97, RMSD 0.92 Å
- 8G6W chain e against the predicted model A1AGK6: TM-score 0.97, RMSD 0.92 Å
- 9AX7 chain e against the predicted model A1AGK6: TM-score 0.97, RMSD 0.92 Å
- 8G6Y chain e against the predicted model A1AGK6: TM-score 0.97, RMSD 0.92 Å
- 9CG5 chain e against the predicted model A1AGK6: TM-score 0.97, RMSD 0.93 Å
- 8URX chain l against the predicted model A1AGK6: TM-score 0.97, RMSD 0.95 Å
- 8URH chain l against the predicted model A1AGK6: TM-score 0.97, RMSD 0.95 Å
- 8UQM chain l against the predicted model A1AGK6: TM-score 0.97, RMSD 0.95 Å
Elsewhere
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