UniProt A0Q5Y3
CRISPR-associated endonuclease Cas9 (A0Q5Y3)
CRISPR-associated endonuclease Cas9 (UniProt A0Q5Y3), EC 3.1.-.-: 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- A0Q5Y3
- Protein
- CRISPR-associated endonuclease Cas9
- EC
- 3.1.-.-
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 20 · 1 record with a druggable one
Structures
5 records of A0Q5Y3 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5B2O | Crystal structure of francisella novicida CAS9 in complex with sgrna and target DNA (tgg pam) | x-ray diffraction | A | — | — |
| 5B2P | Crystal structure of francisella novicida CAS9 in complex with sgrna and target DNA (tga pam) | x-ray diffraction | A | — | — |
| 5B2Q | Crystal structure of Francisella novicida Cas9 RHA in complex with sgRNA and target DNA (TGG PAM) | x-ray diffraction | A | ZN, NA, CL, CA | 20 (best 0.88) |
| 5B2Q | Crystal structure of francisella novicida CAS9 rha in complex with sgrna and target DNA (tgg pam) | x-ray diffraction | A | — | — |
| A0Q5Y3 | AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS9 (A0Q5Y3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5B2O chain A against the predicted model A0Q5Y3: TM-score 1.00, RMSD 0.75 Å
- 5B2P chain A against the predicted model A0Q5Y3: TM-score 1.00, RMSD 0.76 Å
- 5B2Q chain A against the predicted model A0Q5Y3: TM-score 1.00, RMSD 0.76 Å
- 5B2Q chain A against the predicted model A0Q5Y3: TM-score 1.00, RMSD 0.76 Å
Elsewhere
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