UniProt A0AVT1
Ubiquitin-like modifier-activating enzyme 6 (A0AVT1)
Ubiquitin-like modifier-activating enzyme 6 (UniProt A0AVT1), EC 6.2.1.45: 5 experimental structures on GenesisL1, 6 ligands bound, 40 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0AVT1
- Protein
- Ubiquitin-like modifier-activating enzyme 6
- EC
- 6.2.1.45
- Experimental structures
- 5
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 40 · 2 records with a druggable one
Structures
5 records of A0AVT1 in the MolNFT archive: 5 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7PVN | Crystal Structure of Human UBA6 in Complex with ATP | x-ray diffraction | A, B | ATP, MG, CA, CL | 20 (best 0.76) |
| 7PVN | Crystal structure of human UBA6 in complex with ATP | x-ray diffraction | A, B | ATP, MG, CA, CL | — |
| 7PYV | Crystal structure of human UBA6 in complex with the ubiquitin-like modifier FAT10 | x-ray diffraction | A, B | — | — |
| 7SOL | Crystal Structures of the bispecific ubiquitin/FAT10 activating enzyme, Uba6 | x-ray diffraction | A, C | IHP, AMP | 20 (best 0.75) |
| A0AVT1 | AlphaFold monomer V2.0 prediction for ubiquitin-like modifier- activating enzyme 6 (A0AVT1) | — | — | — |
Ligands
Experiment against prediction
- 7PYV chain A against the predicted model P22314: TM-score 0.79, RMSD 4.76 Å
- 7PYV chain B against the predicted model P22314: TM-score 0.79, RMSD 4.78 Å
Elsewhere
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