UniProt A0A6P1C618
Bifunctional lysylphosphatidylglycerol flippase/synthetase MprF (A0A6P1C618)
Bifunctional lysylphosphatidylglycerol flippase/synthetase MprF (UniProt A0A6P1C618): 2 experimental structures on GenesisL1, 4 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A6P1C618
- Protein
- Bifunctional lysylphosphatidylglycerol flippase/synthetase MprF
- Experimental structures
- 2
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 15 · 1 record with a druggable one
Structures
2 records of A0A6P1C618 in the MolNFT archive: 2 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DUW | Cryo-EM structure of the multiple peptide resistance factor (MprF) loaded with two… | electron microscopy | A, B | EV9, LHG, PGT, J4U | 15 (best 0.86) |
| 7DUW | Cryo-EM structure of the multiple peptide resistance factor (mprf) loaded with two… | electron microscopy | A, B | EV9, LHG, PGT, J4U | — |
Ligands
- EV9 · [(2~{R})-3-[[(2~{S})-3-[(2~{S})-2,6-bis(azanyl) hexanoyl]oxy-2-oxidanyl-propoxy]-oxidanyl-phosphoryl]oxy-2-hexadecanoyloxy-propyl] hexadecanoate · in 2 records
- J4U · (2~{R},3~{S},4~{S},5~{S},6~{S})-2-(hydroxymethyl)-6-[(2~{R},3~{S},4~{R},5~{R},6~{R})-2-(hydroxymethyl)-6-[2-[[(2~{R},3~{S},4~{R},5~{R},6~{S})-6-(hydroxymethyl)-5-[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,4-bis(oxidanyl)oxan-2-yl]oxymethyl]-4-[(1~{R},2~{R}, 4~{S},5'~{R},6~{R},7~{R},8~{R},9~{S},12~{S},13~{R}, 16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxy-butoxy]-4,5-bis(oxidanyl)oxa · in 2 records
- LHG · 1,2-dipalmitoyl-phosphatidyl-glycerole · in 2 records
- PGT · (1S)-2-{[{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate · in 2 records
Elsewhere
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