UniProt A0A6M5E0N3
Transmembrane protein 87A,EGFP (A0A6M5E0N3)
Transmembrane protein 87A,EGFP (UniProt A0A6M5E0N3), EC 1.-.-.-: 4 experimental structures on GenesisL1, 5 ligands bound, 12 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A6M5E0N3
- Protein
- Transmembrane protein 87A,EGFP
- EC
- 1.-.-.-
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 12 · 4 records with a druggable one
Structures
4 records of A0A6M5E0N3 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7U8G | Cryo-EM structure of the core human NADPH oxidase NOX2 | electron microscopy | A | POV, NAG, HEM | 2 (best 0.85) |
| 8HTT | Cryo-EM structure of human TMEM87A, gluconate-bound | electron microscopy | B | NAG, GCO | 3 (best 0.82) |
| 8KB4 | Cryo-EM structure of human TMEM87A A308M | electron microscopy | A | NAG, 65I | 3 (best 0.76) |
| 8U1U | Structure of a class A GPCR/agonist complex | electron microscopy | A | NAG | 4 (best 0.78) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
- 65I · (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate · in 1 record
- GCO · D-gluconic acid · in 1 record
- HEM · Protoporphyrin IX containing Fe · in 1 record
- POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · in 1 record
Experiment against prediction
- 7U8G chain A against the predicted model P04839: TM-score 0.98, RMSD 0.94 Å
- 8HTT chain B against the predicted model Q8NBN3: TM-score 0.92, RMSD 2.11 Å
- 8KB4 chain A against the predicted model Q8NBN3: TM-score 0.92, RMSD 2.24 Å
- 8U1U chain A against the predicted model P51685: TM-score 0.75, RMSD 2.61 Å
- 8U1U chain A against the predicted model P22362: TM-score 0.18, RMSD 2.36 Å
Elsewhere
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