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UniProt A0A6J4CX17

2-oxoglutarate/Fe(II)-dependent dioxygenase SptF (A0A6J4CX17)

2-oxoglutarate/Fe(II)-dependent dioxygenase SptF (UniProt A0A6J4CX17): 12 experimental structures on GenesisL1, 6 ligands bound, 49 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A6J4CX17
Protein
2-oxoglutarate/Fe(II)-dependent dioxygenase SptF
Experimental structures
12
Predicted models
0
Ligands
6
Pockets
49 · 4 records with a druggable one

Structures

12 records of A0A6J4CX17 in the MolNFT archive: 12 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7EYRFe(II)/(alpha)ketoglutarate-dependent dioxygenase SptF apox-ray diffractionC, A, B, DFE214 (best 0.66)
7EYRFE(II)/(ALPHA)KETOGLUTARATE-dependent dioxygenase sptf apox-ray diffractionC, A, B, DFE2—
7EYSComplex structure of SptF with Fe, alpha-ketoglutarate, and andiconin Dx-ray diffractionC, A, B, DAKG, 0CC, FE215 (best 0.78)
7EYSComplex structure of sptf with fe, alpha-ketoglutarate, and andiconin Dx-ray diffractionC, A, B, DAKG, 0CC, FE2—
7EYTFe(II)/(alpha)ketoglutarate-dependent dioxygenase SptF with andilesin C and NOGx-ray diffractionC, A, B, DOGA, 0I3, FE2—
7EYTFE(II)/(ALPHA)KETOGLUTARATE-dependent dioxygenase sptf with andilesin C and nogx-ray diffractionC, A, B, DOGA, 0I3, FE2—
7EYUFe(II)/(alpha)ketoglutarate-dependent dioxygenase SptF-N65T mutant with andiconin Dx-ray diffractionB, AOGA, 0CC, FE24 (best 0.86)
7EYUFE(II)/(ALPHA)KETOGLUTARATE-dependent dioxygenase sptf-N65T mutant with andiconin Dx-ray diffractionB, AOGA, 0CC, FE2—
7EYWFe(II)/(alpha)ketoglutarate-dependent dioxygenase SptF with terretonin Cx-ray diffractionC, A, B, DOGA, FE2, 0IP16 (best 0.76)
7EYWFE(II)/(ALPHA)KETOGLUTARATE-dependent dioxygenase sptf with terretonin Cx-ray diffractionC, A, B, DOGA, FE2, 0IP—
7FCBSptF 9 residues truncated mutantx-ray diffractionCOGA, FE2—
7FCBSptf 9 residues truncated mutantx-ray diffractionCOGA, FE2—

Ligands

  • FE2 · Fe (II) ion · in 12 records
  • OGA · N-oxalylglycine · in 8 records
  • 0CC · Andiconin D · in 4 records
  • 0I3 · Andilesin C · in 2 records
  • 0IP · Terretonin C · in 2 records
  • AKG · 2-oxoglutaric acid · in 2 records

Elsewhere

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