UniProt A0A6A5PZI8
CRM1 isoform 1 (A0A6A5PZI8)
CRM1 isoform 1 (UniProt A0A6A5PZI8): 12 experimental structures on GenesisL1, 14 ligands bound, 134 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A6A5PZI8
- Protein
- CRM1 isoform 1
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 14
- Pockets
- 134 · 11 records with a druggable one
Structures
12 records of A0A6A5PZI8 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7CND | NCI-1 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | G6U, CL | 10 (best 0.85) |
| 7CND | Nci-1 in complex with CRM1-ran-RANBP1 | x-ray diffraction | C | G6U, CL | 10 (best 0.85) |
| 7DBG | Yeast CRM1e (apo) in complex with Ran-RanBP1 | x-ray diffraction | C | CL | 12 (best 0.87) |
| 7DBG | Yeast CRM1E (apo) in complex with ran-RANBP1 | x-ray diffraction | C | CL | — |
| 7YPZ | Zafirlukast in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | CL, NA, ZLK | 15 (best 0.84) |
| 8HQ3 | KL1 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | NO3, CL, MI8 | 13 (best 0.85) |
| 8HQ4 | B27 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | CL, M9R | 11 (best 0.85) |
| 8HQ5 | G6 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | CL, MBI | 15 (best 0.85) |
| 8HQ6 | KL2 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | NO3, GLU, CL, MFF | 14 (best 0.85) |
| 8HUF | B28 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | BR, CL, NA, N5X | 9 (best 0.86) |
| 8HUG | F1 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | CL, N59 | 13 (best 0.86) |
| 8ITV | KL2.1 in complex with CRM1-Ran-RanBP1 | x-ray diffraction | C | NO3, CL, Q73 | 12 (best 0.86) |
Ligands
- CL · Chloride ion · in 12 records
- NO3 · Nitrate ion · in 3 records
- G6U · ~{N}-[(~{E})-3-[3,5-bis(trifluoromethyl)phenyl]sulfinylprop-2-enyl]-3-methyl-butan-1-amine · in 2 records
- NA · Sodium ion · in 2 records
- BR · Bromide ion · in 1 record
- GLU · Glutamic acid · in 1 record
- M9R · 3-[(4-fluorophenyl)carbonylamino]-4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]benzoic acid · in 1 record
- MBI · 3-[(4-bromophenyl)carbonylamino]-4-[4-(5-chloranyl-2-methyl-phenyl)piperazin-1-yl]benzoic acid · in 1 record
- MFF · methyl (3~{S},5~{R},6~{E},8~{Z},10~{R},12~{E},14~{E},16~{S})-3,16-bis(azanyl)-8,10,12-trimethyl-16-[(2~{S},4~{R},5~{S},6~{S})-5-methyl-4-oxidanyl-6-[(~{E})-prop-1-enyl]oxan-2-yl]-5-oxidanyl-hexadeca-6,8,12,14-tetraenoate · in 1 record
- MI8 · methyl (3~{S},5~{R},6~{E},8~{Z},10~{R},12~{E},14~{E},16~{R})-3,16-bis(azanyl)-8,10,12-trimethyl-16-[(2~{S},4~{R},5~{S},6~{S})-5-methyl-4-oxidanyl-6-[(~{E})-prop-1-enyl]oxan-2-yl]-5-oxidanyl-hexadeca-6,8,12,14-tetraenoate · in 1 record
- N59 · 4-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(3-fluorophenyl)sulfonylamino]benzoic acid · in 1 record
- N5X · 3-[(4-chlorophenyl)carbonylamino]-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]benzoic acid · in 1 record
- Q73 · (3~{S},5~{R},6~{E},8~{Z},10~{R},12~{E},14~{E},16~{S})-3,16-bis(azanyl)-8,10,12-trimethyl-16-[(2~{S},4~{R},5~{S},6~{S})-5-methyl-4-oxidanyl-6-[(~{E})-prop-1-enyl]oxan-2-yl]-5-oxidanyl-hexadeca-6,8,12,14-tetraenoic acid · in 1 record
- ZLK · zafirlukast · in 1 record
Elsewhere
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