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Ligand · MI8

MI8 · methyl (3~{S},5~{R},6~{E},8~{Z},10~{R},12~{E},14~{E},16~{R})-3,16-bis(azanyl)-8,10,12-trimethyl-16-[(2~{S},4~{R},5~{S},6~{S})-5-methyl-4-oxidanyl-6-[(~{E})-prop-1-enyl]oxan-2-yl]-5-oxidanyl-hexadeca-6,8,12,14-tetraenoate

MI8, methyl (3~{S},5~{R},6~{E},8~{Z},10~{R},12~{E},14~{E},16~{R})-3,16-bis(azanyl)-8,10,12-trimethyl-16-[(2~{S},4~{R},5~{S},6~{S})-5-methyl-4-oxidanyl-6-[(~{E})-prop-1-enyl]oxan-2-yl]-5-oxidanyl-hexadeca-6,8,12,14-tetraenoate (C29 H48 N2…

Component
MI8
Formula
C29 H48 N2 O5
Class
ligand
Structures
1
PDB entries
1

Binding sites

MI8 in 1 structure; the first of them:

  • 8HQ3 · KL1 in complex with CRM1-Ran-RanBP1 · MI8 C1124 · binds VAL529, ILE532, LYS533, LEU536, CYS539, GLU540, LYS545, LYS548 and 12 more

Residues it binds most

LYS 1, PHE 1, ALA 1, GLU 1, ILE 1, VAL 1, CYS 1, HIS 1, LEU 1, MET 1 (residue and the binding sites it lines).

Found with

  • GTP · Guanosine-5'-triphosphate
  • MG · Magnesium ion
  • CL · Chloride ion
  • NO3 · Nitrate ion
  • DMS · Dimethyl sulfoxide
  • GOL · Glycerol

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