UniProt A0A630AQ07
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (A0A630AQ07)
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (UniProt A0A630AQ07), EC 5.3.1.16: 10 experimental structures on GenesisL1, 4 ligands bound, 4 pockets. Binding sites, pockets…
- UniProt
- A0A630AQ07
- Protein
- 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]…
- EC
- 5.3.1.16
- Experimental structures
- 10
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 4 · 4 records with a druggable one
Structures
10 records of A0A630AQ07 in the MolNFT archive: 10 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5A5W | Crystal structure of Salmonella enterica HisA D7N D176A with ProFAR | x-ray diffraction | A | GUO | 1 (best 0.84) |
| 5AC6 | S.enterica HisA mutant D10G, dup13-15, Q24L, G102A | x-ray diffraction | A | — | — |
| 5AC7 | S. enterica HisA with mutations D7N, D10G, dup13-15 | x-ray diffraction | A, B | — | — |
| 5AC8 | S. enterica HisA with mutations D10G, dup13-15, G102A | x-ray diffraction | A | SO4 | 1 (best 0.68) |
| 5AHE | Crystal structure of Salmonella enterica HisA | x-ray diffraction | A | — | — |
| 5G1T | S. enterica HisA mutant dup13-15, D10G | x-ray diffraction | A | PO4 | 1 (best 0.68) |
| 5G1Y | S. enterica HisA mutant D10G, dup13-15,V14:2M, Q24L, G102 | x-ray diffraction | A | SO4 | — |
| 5G2I | S. enterica HisA mutant Dup13-15(VVR) | x-ray diffraction | A | PO4, NA | — |
| 5G2W | S. enterica HisA mutant D10G, G102A | x-ray diffraction | A | SO4 | 1 (best 0.63) |
| 5G4E | S. enterica HisA mutant D10G, Dup13-15, Q24L, G102A, V106L | x-ray diffraction | A, B | SO4, NA | — |
Ligands
- SO4 · Sulfate ion · in 4 records
- NA · Sodium ion · in 2 records
- PO4 · Phosphate ion · in 2 records
- GUO · [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S, 5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate · in 1 record
Elsewhere
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