GUO · [(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S, 5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate

Binding sites

GUO in 7 structures; the first of them:

• 5A5W · Crystal structure of Salmonella enterica HisA D7N D176A with ProFAR · GUO A1246 · binds ALA5, ASN7, LEU16, GLY19, TYR21, HIS47, VAL49, LEU51 and 29 more
• 5ABT · S.enterica HisA mutant D7N, G102A, V106M, D176A · GUO A1247 · binds ALA5, ASN7, LEU16, GLY19, TYR21, HIS47, VAL49, LEU51 and 29 more
• 5AHF · Crystal structure of Salmonella enterica HisA D7N with ProFAR · GUO A1245 · binds ALA5, ASN7, ARG15, LEU16, HIS47, VAL49, LEU51, GLY80 and 17 more
• 5G4W · S. enterica HisA mutant D7N, D10G, Dup13-15 (VVR) with substrate ProFAR · GUO A1245 · binds ALA5, ASN7, ARG15, VAL15A, HIS47, VAL49, LEU51, GLY80 and 18 more
• 7AC8 · Molecular basis for the unique allosteric activation mechanism of the heterodimeric… · GUO A301 · binds CYS9, ASP11, LEU50, ILE52, GLY81, GLY82, ILE83, ILE102 and 19 more
• 9FCF · Medicago truncatula 5'-ProFAR isomerase (HISN3) D57N mutant in complex with ProFAR · GUO A401 · binds CYS55, ASN57, GLN65, GLY68, LEU71, HIS108, ILE110, LEU112 and 25 more
• 7AC8 · Molecular basis for the unique allosteric activation mechanism of the heterodimeric… · GUO A301 · binds LEU50, ILE52, GLY81, GLY82, ASN103, THR104, ASP130, SER144 and 11 more

Residues it binds most

GLY 9, SER 9, ALA 9, LEU 9, VAL 5, ILE 9, ASP 9, THR 8, ARG 7, ASN 9 (residue and the binding sites it lines).

Found with

• PO4 · Phosphate ion
• GOL · Glycerol
• GLN · Glutamine
• NA · Sodium ion
• CL · Chloride ion