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UniProt A0A4U3MLJ4

Hydroxymethylglutaryl-CoA reductase, degradative (A0A4U3MLJ4)

Hydroxymethylglutaryl-CoA reductase, degradative (UniProt A0A4U3MLJ4), EC 1.1.1.88: 2 experimental structures on GenesisL1, 3 ligands bound, 13 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A4U3MLJ4
Protein
Hydroxymethylglutaryl-CoA reductase, degradative
EC
1.1.1.88
Experimental structures
2
Predicted models
0
Ligands
3
Pockets
13 · 2 records with a druggable one

Structures

2 records of A0A4U3MLJ4 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7M3HTargeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitorx-ray diffractionA, BYPV, SO4, CA5 (best 0.79)
7M66Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitorx-ray diffractionA, B, C, DSO4, CA8 (best 0.84)

Ligands

  • CA · Calcium ion · in 2 records
  • SO4 · Sulfate ion · in 2 records
  • YPV · 5-[(4-butylphenyl)sulfamoyl]-2-hydroxybenzoic acid · in 1 record

Elsewhere

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