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UniProt A0A486EJ79

DNA topoisomerase 4 subunit B, DNA topoisomerase 4 subunit A chimera (A0A486EJ79)

DNA topoisomerase 4 subunit B, DNA topoisomerase 4 subunit A chimera (UniProt A0A486EJ79), EC 5.6.2.2: 2 experimental structures on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in…

UniProt
A0A486EJ79
Protein
DNA topoisomerase 4 subunit B, DNA topoisomerase 4 subunit A chimera
EC
5.6.2.2
Experimental structures
2
Predicted models
0
Ligands
2
Pockets
20 · 1 record with a druggable one

Structures

2 records of A0A486EJ79 in the MolNFT archive: 2 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7LHZK. pneumoniae Topoisomerase IV (ParE-ParC) in complex with DNA and…x-ray diffractionC, D, A, BMG, Y2120 (best 0.87)
7LHZK. pneumoniae topoisomerase IV (pare-parc) in complex with DNA and…x-ray diffractionC, D, A, BMG, Y21—

Ligands

  • MG · Magnesium ion · in 2 records
  • Y21 · (3S)-10-[(3R)-3-(1-aminocyclopropyl)pyrrolidin-1-yl]-9-fluoro-3-methyl-5-oxo-2,3-dihydro-5H-[1,4]oxazino[2,3, 4-ij]quinoline-6-carboxylic acid · in 2 records

Elsewhere

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