UniProt A0A447EB45
Inhibitor of Type II CRISPR-Cas system (A0A447EB45)
Inhibitor of Type II CRISPR-Cas system (UniProt A0A447EB45): 2 experimental structures on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A447EB45
- Protein
- Inhibitor of Type II CRISPR-Cas system
- Experimental structures
- 2
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 8 · 2 records with a druggable one
Structures
2 records of A0A447EB45 in the MolNFT archive: 2 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8KBJ | Structure of HgmTad2 complexed with 1',2'-cADPR | x-ray diffraction | A, C, D, B | MF6 | 4 (best 0.79) |
| 8KBK | Structure of AcrIIA7 complexed with 1',2'-cADPR and cGG | x-ray diffraction | A, D, B, C | MF6, C2E | 4 (best 0.80) |
Ligands
- MF6 · (1S,3R,4R,6R,9S,11R,14R,15S,16R,18R)-4-(6-amino-9H-purin-9-yl)-9,11,15,16,18-pentahydroxy-2,5,8,10,12,17-hexaoxa-9lambda~5~,11lambda~5~-diphosphatricyclo[12.2.1.1~3,6~]octadecane-9,11-dione · in 2 records
- C2E · 9,9'-[(2r,3r,3as,5s,7ar,9r,10r,10as,12s,14ar)-3,5,10, 12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3, 2-D:3',2'-J][1,3,7,9,2, 8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one) · in 1 record
Elsewhere
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