UniProt A0A411J078

MHC class I antigen (A0A411J078)

MHC class I antigen (UniProt A0A411J078): 37 experimental structures on GenesisL1, 6 ligands bound, 200 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: A0A411J078
Protein: MHC class I antigen
Experimental structures: 37
Predicted models: 0
Ligands: 6
Pockets: 200 · 24 records with a druggable one

Structures

37 records of A0A411J078 in the MolNFT archive: 37 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6XQA	Crystal Structure of HLA A*2402 in complex with TYQWVLKNL, an 9-mer epitope from Influenza B virus	x-ray diffraction	A, D	MG	9 (best 0.76)
6XQA	Crystal structure of HLA A*2402 in complex with tyqwvlknl, an 9-mer epitope from influenza B virus	x-ray diffraction	A, D	MG	—
7EJL	Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-2) spike protein	x-ray diffraction	A	—	4 (best 0.69)
7EJL	Complex structure of HLA-A*2402 with the peptide from HCOV(COV-2) spike protein	x-ray diffraction	A	—	—
7EJM	Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-229E) spike protein	x-ray diffraction	A	—	—
7EJM	Complex structure of HLA-A*2402 with the peptide from HCOV(COV-229E) spike protein	x-ray diffraction	A	—	—
7EJN	Complex Structure of HLA-A*2402 with the Peptide from HCoV(CoV-HKU1) spike protein	x-ray diffraction	A	—	4 (best 0.68)
7EJN	Complex structure of HLA-A*2402 with the peptide from HCOV(COV-HKU1) spike protein	x-ray diffraction	A	—	—
7JYU	Crystal Structure of HLA-A*2402 in complex with IYFSPIRVTF, an 10-mer epitope from Influenza B virus	x-ray diffraction	A, D	MG	8 (best 0.74)
7JYU	Crystal structure of HLA-A*2402 in complex with iyfspirvtf, an 10-mer epitope from influenza B virus	x-ray diffraction	A, D	MG	—
7JYV	Crystal Structure of HLA A*2402 in complex with YFSPIRVTF, an 9-mer influenza epitope	x-ray diffraction	A	MG	4 (best 0.67)
7JYV	Crystal structure of HLA A*2402 in complex with yfspirvtf, an 9-mer influenza epitope	x-ray diffraction	A	MG	—
7JYW	Crystal Structure of HLA A*2402 in complex with TYQWIIRNW, an 9-mer influenza epitope	x-ray diffraction	A	CA, NA	4 (best 0.69)
7JYW	Crystal structure of HLA A*2402 in complex with tyqwiirnw, an 9-mer influenza epitope	x-ray diffraction	A	CA, NA	—
7JYX	Crystal Structure of HLA A*2402 in complex with TYQWIIRNWET, an 11-mer epitope from Influenza	x-ray diffraction	A, D	—	7 (best 0.68)
7JYX	Crystal structure of HLA A*2402 in complex with tyqwiirnwet, an 11-mer epitope from influenza	x-ray diffraction	A, D	—	—
7K80	KIR3DL1001 in complex with HLA-A24:02 presenting the RYPLTFGW peptide	x-ray diffraction	A, D	—	10 (best 0.77)
7K80	KIR3DL1001 in complex with HLA-A24:02 presenting the rypltfgw peptide	x-ray diffraction	A, D	—	—
7K81	KIR3DL1005 in complex with HLA-A24:02 presenting the RYPLTFGW peptide	x-ray diffraction	A	—	6 (best 0.74)
7K81	KIR3DL1005 in complex with HLA-A24:02 presenting the rypltfgw peptide	x-ray diffraction	A	—	—
7NMD	Human Major Histocompatibility Complex A24 Allele presenting QLPRLFPLL	x-ray diffraction	A, D	SO4	10 (best 0.71)
7NME	Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR	x-ray diffraction	A	SO4	6 (best 0.70)
7NMF	Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR, monoclinic form	x-ray diffraction	A	—	7 (best 0.70)
7NMG	Human MHC Class I, A24 Allele presenting LWM, Complex with 4C6 TCR	x-ray diffraction	A	SO4	8 (best 0.72)
7SRK	Single chain trimer HLA-A*24:02 (Y108C, A163C) with 8mer peptide YPPVPETF	x-ray diffraction	A, C	—	11 (best 0.76)
7WT3	Crystal structure of HLA-A*2402 complexed with 4-mer lipopeptide	x-ray diffraction	A, D	ZN	11 (best 0.71)
7WT3	Crystal structure of HLA-A*2402 complexed with 4-mer lipopeptide	x-ray diffraction	A, D	MYR, ZN	—
7WT4	Crystal structure of HLA-A*2402 complexed with 8-mer Influenza PB1 peptide	x-ray diffraction	A, D	ZN	10 (best 0.71)
7WT4	Crystal structure of HLA-A*2402 complexed with 8-mer influenza PB1 peptide	x-ray diffraction	A, D	ZN	—
8RJH	HLA A*2402-NF9_6F pMHC complex	x-ray diffraction	A, D, G, J, M, P	—	20 (best 0.70)
8RJI	HLA A*2402-NF9_5R pMHC complex	x-ray diffraction	A, D, G, J	—	20 (best 0.73)
8SBK	Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI (ATG2A).	x-ray diffraction	A	SO4	4 (best 0.68)
8SBL	Structure of HLA-A*24:02 in complex with peptide, LYLPVRVLI	x-ray diffraction	A, D, G, J	—	17 (best 0.72)
9BL5	KIR3DL1001 in complex with HLA-A24:02 presenting the TW9 peptide	x-ray diffraction	A	—	5 (best 0.74)
9BL6	KIR3DL1114 in complex with HLA-A24:02 presenting the TW9 peptide	x-ray diffraction	A	—	6 (best 0.68)
9BL9	KIR3DL1114 in complex with HLA-A24:02 presenting the NEF peptide	x-ray diffraction	A	—	5 (best 0.74)
9BLA	KIR3DL1086 in complex with HLA-A24:02 presenting the NEF peptide	x-ray diffraction	A	—	4 (best 0.72)

Ligands

MG · Magnesium ion · in 6 records
SO4 · Sulfate ion · in 4 records
ZN · Zinc ion · in 4 records
CA · Calcium ion · in 2 records
NA · Sodium ion · in 2 records
MYR · Myristic acid · in 1 record

Experiment against prediction

7SRK chain C against the predicted model P16213: TM-score 0.26, RMSD 0.56 Å
7SRK chain A against the predicted model P16213: TM-score 0.26, RMSD 1.31 Å
7SRK chain A against the predicted model Q6NSI4: TM-score 0.28, RMSD 7.62 Å
7SRK chain C against the predicted model Q6NSI4: TM-score 0.28, RMSD 7.47 Å

Elsewhere

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