UniProt A0A2X0THW2
DNA topoisomerase 2 (A0A2X0THW2)
DNA topoisomerase 2 (UniProt A0A2X0THW2): 9 experimental structures on GenesisL1, 3 ligands bound, 145 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A2X0THW2
- Protein
- DNA topoisomerase 2
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 145 · 9 records with a druggable one
Structures
9 records of A0A2X0THW2 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8J9Y | cryo-EM structure of viral topoisomerase in conformation 1 | electron microscopy | B, A | — | 18 (best 0.78) |
| 8KGL | Structure of African swine fever virus topoisomerase II | electron microscopy | A, B | — | 19 (best 0.84) |
| 8KGM | Structure of African swine fever virus topoisomerase II in complex with dsDNA | electron microscopy | A, B | — | 20 (best 0.86) |
| 8KGN | Structure of African swine fever virus topoisomerase II in complex with dsDNA | electron microscopy | A, B | — | 20 (best 0.86) |
| 8KGP | Structure of African swine fever virus topoisomerase II in complex with dsDNA | electron microscopy | B, A | — | 19 (best 0.82) |
| 8KGR | Structure of African swine fever virus topoisomerase II in complex with dsDNA | electron microscopy | A, B | MG | 20 (best 0.84) |
| 8KGS | Structure of African swine fever virus topoisomerase II in complex with dsDNA | x-ray diffraction | A | MG, ANP | 4 (best 0.74) |
| 8KGT | Structure of African swine fever virus topoisomerase II in complex with dsDNA | x-ray diffraction | A | ADP | 5 (best 0.73) |
| 8WWO | Crystal structure of the AFSV topoisomerase ATPase domain in complex with AMPPNP | x-ray diffraction | A, B, C, D | ANP, MG | 20 (best 0.83) |
Ligands
Elsewhere
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