UniProt A0A2H4A2U9
Protein CYP51 (A0A2H4A2U9)
Protein CYP51 (UniProt A0A2H4A2U9): 10 experimental structures on GenesisL1, 7 ligands bound, 37 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A2H4A2U9
- Protein
- Protein CYP51
- Experimental structures
- 10
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 37 · 4 records with a druggable one
Structures
10 records of A0A2H4A2U9 in the MolNFT archive: 10 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AYC | Naegleria fowleri CYP51-itraconazole complex | x-ray diffraction | A | HEM, 1YN | — |
| 6AYC | Naegleria fowleri CYP51-itraconazole complex | x-ray diffraction | A | HEM, 1YN | — |
| 7RKR | Naegleria fowleri CYP51 (NfCYP51) complex with (S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl… | x-ray diffraction | A | HEM, L49, CA | 6 (best 0.87) |
| 7RKR | Naegleria fowleri CYP51 (NFCYP51) complex with (S)-1-(4-fluorophenyl)- 2-(1H-imidazol-1-YL)ETHYL… | x-ray diffraction | A | HEM, L49, CA | — |
| 7RKT | Naegleria fowleri CYP51 (NfCYP51) complex with (S)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl… | x-ray diffraction | A | HEM, 5UR | 6 (best 0.86) |
| 7RKT | Naegleria fowleri CYP51 (NFCYP51) complex with (S)-1-(2,4… | x-ray diffraction | A | HEM | — |
| 7RKW | Naegleria fowleri CYP51(NfCYP51) complex with (S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl… | x-ray diffraction | A | HEM, 5TV | 5 (best 0.86) |
| 7RKW | Naegleria fowleri CYP51(NFCYP51) complex with (S)-1-(4-fluorophenyl)- 2-(1H-imidazol-1-YL)ETHYL… | x-ray diffraction | A | HEM | — |
| 7RTQ | Sterol 14alpha demethylase (CYP51) from Naegleria fowleri in complex with an inhibitor… | x-ray diffraction | A, B, C, D | HEM, 7PW | 20 (best 0.87) |
| 7RTQ | Sterol 14ALPHA demethylase (CYP51) from naegleria fowleri in complex with an inhibitor… | x-ray diffraction | A, B, C, D | HEM, 7PW | — |
Ligands
- HEM · Protoporphyrin IX containing Fe · in 10 records
- 1YN · 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one · in 2 records
- 7PW · N-[(1R)-2-(1H-imidazol-1-yl)-1-(3,4',5-trifluoro[1,1'-biphenyl]-4-yl)ethyl]-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide · in 2 records
- CA · Calcium ion · in 2 records
- L49 · (1S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate · in 2 records
- 5TV · (1S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3,5-dichlorobenzoate · in 1 record
- 5UR · (1S)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate · in 1 record
Elsewhere
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