UniProt A0A2A9IR05
Pyruvate carboxylase (A0A2A9IR05)
Pyruvate carboxylase (UniProt A0A2A9IR05), EC 6.4.1.1: 10 experimental structures on GenesisL1, 10 ligands bound, 76 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A2A9IR05
- Protein
- Pyruvate carboxylase
- EC
- 6.4.1.1
- Experimental structures
- 10
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 76 · 8 records with a druggable one
Structures
10 records of A0A2A9IR05 in the MolNFT archive: 10 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7ZYY | Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | electron microscopy | A, B, C, D | MG, MN, ADP, ACO, PYR, BCT | 20 (best 0.86) |
| 7ZYZ | Cryo-EM structure of "CT oxa" conformation of Lactococcus lactis pyruvate carboxylase with… | electron microscopy | A | MN, OAA | 4 (best 0.66) |
| 7ZZ0 | Cryo-EM structure of "CT empty" conformation of Lactococcus lactis pyruvate carboxylase with… | electron microscopy | A | MG, MN | 3 (best 0.71) |
| 7ZZ1 | Cryo-EM structure of "CT react" conformation of Lactococcus lactis pyruvate carboxylase with… | electron microscopy | A, B | MG, MN, OAA, BTN | — |
| 7ZZ2 | Cryo-EM structure of "CT pyr" conformation of Lactococcus lactis pyruvate carboxylase with… | electron microscopy | A | MG, MN, PYR | 4 (best 0.69) |
| 7ZZ3 | Cryo-EM structure of "BC react" conformation of Lactococcus lactis pyruvate carboxylase with… | electron microscopy | A, B, C, D | BTN, MG, MN, ATP, ACO, PYR | 20 (best 0.88) |
| 7ZZ4 | Cryo-EM structure of "BC closed" conformation of Lactococcus lactis pyruvate carboxylase with… | electron microscopy | A | ATP, MG, ACO | 3 (best 0.78) |
| 7ZZ5 | Cryo-EM structure of "BC open" conformation of Lactococcus lactis pyruvate carboxylase with… | electron microscopy | A | ACO, BCT | 2 (best 0.70) |
| 7ZZ6 | Cryo-EM structure of "CT-CT dimer" of Lactococcus lactis pyruvate carboxylase with acetyl-CoA | electron microscopy | D, A | MG, MN, PYR | — |
| 7ZZ8 | Cryo-EM structure of Lactococcus lactis pyruvate carboxylase with acetyl-CoA and cyclic di-AMP | electron microscopy | A, B, C, D | MG, MN, ADP, ACO, PYR, 2BA | 20 (best 0.88) |
Ligands
- MG · Magnesium ion · in 8 records
- MN · Manganese (II) ion · in 8 records
- ACO · Acetyl coenzyme *A · in 5 records
- PYR · Pyruvic acid · in 5 records
- ADP · Adenosine-5'-diphosphate · in 3 records
- BCT · Bicarbonate ion · in 3 records
- ATP · Adenosine-5'-triphosphate · in 2 records
- BTN · Biotin · in 2 records
- OAA · Oxaloacetate ion · in 2 records
- 2BA · (2r,3r,3as,5r,7ar,9r,10r,10as,12r,14ar)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-D:3', 2'-J][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5, 10,12-tetrol 5,12-dioxide · in 1 record
Elsewhere
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