UniProt A0A1X8XLE9
Ancestral Glucocorticoid Receptor2 (A0A1X8XLE9)
Ancestral Glucocorticoid Receptor2 (UniProt A0A1X8XLE9): 12 experimental structures on GenesisL1, 8 ligands bound, 50 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A1X8XLE9
- Protein
- Ancestral Glucocorticoid Receptor2
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 50 · 8 records with a druggable one
Structures
12 records of A0A1X8XLE9 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6W9K | Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with… | x-ray diffraction | A | TUA | 3 (best 0.82) |
| 6W9K | Structure of the ancestral glucocorticoid receptor 2 ligand binding domain in complex with… | x-ray diffraction | A | TUA | — |
| 6W9L | Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with… | x-ray diffraction | A | TUS | 3 (best 0.84) |
| 6W9L | Structure of the ancestral glucocorticoid receptor 2 ligand binding domain in complex with… | x-ray diffraction | A | TUS | — |
| 6W9M | Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with… | x-ray diffraction | A | TUV | 4 (best 0.82) |
| 6W9M | Structure of the ancestral glucocorticoid receptor 2 ligand binding domain in complex with… | x-ray diffraction | A | TUV | — |
| 7YXC | Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment | x-ray diffraction | A | DEX, CO3 | 3 (best 0.85) |
| 7YXD | Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment | x-ray diffraction | A, D, H, L | DEX, NA | 14 (best 0.84) |
| 7YXN | Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment | x-ray diffraction | A, C | DEX | — |
| 7YXO | Crystal structure of WT AncGR2-LBD bound to dexamethasone and SHP coregulator fragment | x-ray diffraction | A, C, E | DEX, CPS, SO4 | 11 (best 0.85) |
| 7YXP | Crystal structure of WT AncGR2-LBD WT bound to dexamethasone and SHP coregulator fragment | x-ray diffraction | A | DEX | 4 (best 0.85) |
| 7YXR | Crystal structure of mutant AncGR2-LBD (Y545A) bound to dexamethasone and SHP coregulator fragment | x-ray diffraction | A, C | DEX | 8 (best 0.83) |
Ligands
- DEX · Dexamethasone · in 6 records
- TUA · prednisolone · in 2 records
- TUS · (4ar,4bs,5s,6as,6bs,9ar,10as,10bs)-5-hydroxy-6B-(hydroxyacetyl)-4A,6A,8-trimethyl-4A,4B,5,6,6A,6B,9A, 10,10A,10B,11,12-dodecahydro-2H-naphtho[2',1':4, 5]indeno[1,2-d][1,3]oxazol-2-one · in 2 records
- TUV · vamorolone · in 2 records
- CO3 · Carbonate ion · in 1 record
- CPS · 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate · in 1 record
- NA · Sodium ion · in 1 record
- SO4 · Sulfate ion · in 1 record
Elsewhere
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