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UniProt A0A1I7NFD7

Piwi domain-containing protein (A0A1I7NFD7)

Piwi domain-containing protein (UniProt A0A1I7NFD7): 16 experimental structures on GenesisL1, 3 ligands bound, 193 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A1I7NFD7
Protein
Piwi domain-containing protein
Experimental structures
16
Predicted models
0
Ligands
3
Pockets
193 · 16 records with a druggable one

Structures

16 records of A0A1I7NFD7 in the MolNFT archive: 16 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8IFKCryo-EM structure of monomeric SPARTA gRNA-ssDNA target complexelectron microscopyBMG7 (best 0.85)
8IFLCryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 1electron microscopyB, G, K, OMG14 (best 0.86)
8IFMCryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 2electron microscopyB, G, K, OMG14 (best 0.86)
8ISYCryo-EM structure of free-state Crt-SPARTAelectron microscopyA—11 (best 0.79)
8ISZCryo-EM structure of Crt-SPARTA-gRNA-tDNA monomerelectron microscopyA—14 (best 0.84)
8IT0Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-2)electron microscopyA, E—18 (best 0.86)
8IT1Cryo-EM structure of Crt-SPARTA-gRNA-tDNA tetramer (NADase active form)electron microscopyA, E, I, M—17 (best 0.87)
8J84Short ago complexed with TIR-APAZelectron microscopyA—8 (best 0.86)
8J8HSPARTA monomer bound with guide-target, state 2electron microscopyAMG6 (best 0.84)
8J9GCrtSPARTA hetero-dimer bound with guide-target, state 1electron microscopyAMG11 (best 0.82)
8J9PSPARTA dimer bound with guide-targetelectron microscopyA, CMG11 (best 0.82)
8JAYCrtSPARTA Octamer bound with guide-targetelectron microscopyC, A, I, MMG14 (best 0.85)
8K34Cryo-EM structure of SPARTA gRNA binary complexelectron microscopyBMG7 (best 0.75)
8K9GCryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-1)electron microscopyA, E—17 (best 0.83)
8U72Cryo-EM structure of the SPARTA oligomer with guide RNA and target DNAelectron microscopyI, E, C, GMG14 (best 0.82)
8U7BCrystal structure of Apo form of Short Prokaryotic Argonaute TIR-APAZ (SPARTA) heterodimerx-ray diffractionCPRO, MN10 (best 0.75)

Ligands

  • MG · Magnesium ion · in 9 records
  • MN · Manganese (II) ion · in 1 record
  • PRO · Proline · in 1 record

Elsewhere

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