UniProt A0A145BYP4
Ketol-acid reductoisomerase (NADP(+)) (A0A145BYP4)
Ketol-acid reductoisomerase (NADP(+)) (UniProt A0A145BYP4), EC 1.1.1.86: 8 experimental structures on GenesisL1, 6 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A145BYP4
- Protein
- Ketol-acid reductoisomerase (NADP(+))
- EC
- 1.1.1.86
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 18 · 4 records with a druggable one
Structures
8 records of A0A145BYP4 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5W3K | Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex NADPH, Mg2+ and… | x-ray diffraction | A, B | 9TY, MG, NDP | 4 (best 0.74) |
| 5W3K | Crystal structure of staphylococcus aureus ketol-acid reductoisomerase in complex NADPH, MG2+ and… | x-ray diffraction | A, B | 9TY, MG, NDP | — |
| 6VO2 | Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex with Mg, NADPH… | x-ray diffraction | A, B | MG, R67, NDP | 4 (best 0.75) |
| 6VO2 | Crystal structure of staphylococcus aureus ketol-acid reductoisomerase in complex with mg, NADPH… | x-ray diffraction | A, B | MG, R67, NDP | — |
| 7KE2 | Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex with Mg2+ and… | x-ray diffraction | B, A | MG, WBY | 6 (best 0.74) |
| 7KE2 | Crystal structure of staphylococcus aureus ketol-acid reductoisomerase in complex with MG2+ and… | x-ray diffraction | B, A | MG, WBY | — |
| 7KH7 | Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase in complex with Mg2+, NADPH… | x-ray diffraction | A, B | NAP, NDP, MG, WBY | 4 (best 0.76) |
| 7KH7 | Crystal structure of staphylococcus aureus ketol-acid reductoisomerase in complex with MG2+, NADPH… | x-ray diffraction | A, B | NAP, NDP, MG, WBY | — |
Ligands
- MG · Magnesium ion · in 8 records
- NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 6 records
- WBY · 6-hydroxy-2-methyl[1,3]thiazolo[4,5-d]pyrimidine-5, 7(4H,6H)-dione · in 4 records
- 9TY · cyclopropane-1,1-dicarboxylic acid · in 2 records
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · in 2 records
- R67 · 3-(methylsulfonyl)-2-oxopropanoic acid · in 2 records
Elsewhere
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