UniProt A0A0T9EA39
Beta-lactamase (A0A0T9EA39)
Beta-lactamase (UniProt A0A0T9EA39), EC 3.5.2.6: 20 experimental structures on GenesisL1, 10 ligands bound, 46 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A0T9EA39
- Protein
- Beta-lactamase
- EC
- 3.5.2.6
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 46 · 8 records with a druggable one
Structures
20 records of A0A0T9EA39 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NJ2 | Crystal structure of BlaC from Mycobacterium tuberculosis bound to phosphate | x-ray diffraction | A, B | PO4, ETE, AE4 | 5 (best 0.51) |
| 5NJ2 | Crystal structure of blac from mycobacterium tuberculosis bound to phosphate | x-ray diffraction | A, B | PO4, ETE, AE4 | — |
| 5OYO | Crystal structure of BlaC from Mycobacterium tuberculosis | x-ray diffraction | A, B | — | 5 (best 0.55) |
| 5OYO | Crystal structure of blac from mycobacterium tuberculosis | x-ray diffraction | A, B | — | — |
| 6H28 | Structure of S70A BlaC from Mycobacterium tuberculosis obtained from crystals produced in the… | x-ray diffraction | A, B | — | 4 (best 0.48) |
| 6H28 | Structure of S70A blac from mycobacterium tuberculosis obtained from crystals produced in the… | x-ray diffraction | A, B | — | — |
| 6H2A | Structure of S70A BlaC from Mycobacterium tuberculosis obtained from crystals produced in the… | x-ray diffraction | A, B, C | TAM, PO4 | 7 (best 0.71) |
| 6H2A | Structure of S70A blac from mycobacterium tuberculosis obtained from crystals produced in the… | x-ray diffraction | A, B, C | TAM, PO4 | — |
| 6H2C | Structure of BlaC from Mycobacterium tuberculosis bound to the trans-enamine adduct derived from… | x-ray diffraction | A, B | ISS, CO2 | 4 (best 0.52) |
| 6H2C | Structure of blac from mycobacterium tuberculosis bound to the trans- enamine adduct derived from… | x-ray diffraction | A, B | ISS, CO2 | — |
| 6H2G | Structure of BlaC from Mycobacterium tuberculosis bound to the propionaldehyde ester adduct of… | x-ray diffraction | A, B | FK2 | 5 (best 0.56) |
| 6H2G | Structure of blac from mycobacterium tuberculosis bound to the propionaldehyde ester adduct of… | x-ray diffraction | A, B | FK2 | — |
| 6H2H | Structure of BlaC from Mycobacterium tuberculosis covalently bound to avibactam. | x-ray diffraction | A, B | NXL | 5 (best 0.60) |
| 6H2H | Structure of blac from mycobacterium tuberculosis covalently bound to avibactam. | x-ray diffraction | A, B | — | — |
| 6H2I | Structure of BlaC from Mycobacterium tuberculosis bound to the trans-enamine adduct of tazobactam. | x-ray diffraction | A, B | TBE | 5 (best 0.54) |
| 6H2I | Structure of blac from mycobacterium tuberculosis bound to the trans- enamine adduct of tazobactam. | x-ray diffraction | A, B | TBE | — |
| 6H2K | Structure of BlaC from Mycobacterium tuberculosis bound to the trans-enamine adduct of sulbactam. | x-ray diffraction | A, B | TSL | 5 (best 0.58) |
| 6H2K | Structure of blac from mycobacterium tuberculosis bound to the trans- enamine adduct of sulbactam. | x-ray diffraction | A, B | TSL | — |
| 6N14 | Phosphoserine BlaC, Class A serine beta-lactamase from Mycobacterium tuberculosis | x-ray diffraction | A | PO4 | 1 (best 0.31) |
| 6N14 | Phosphoserine blac, class a serine beta-lactamase from mycobacterium tuberculosis | x-ray diffraction | A | PO4 | — |
Ligands
- PO4 · Phosphate ion · in 6 records
- AE4 · 3,6,9,12,15-pentaoxaheptadecan-1-ol · in 2 records
- CO2 · Carbon dioxide · in 2 records
- ETE · 2-{2-[2-2-(methoxy-ethoxy)-ethoxy]-ethoxy}-ethanol · in 2 records
- FK2 · 3-oxidanylidenepropanoic acid · in 2 records
- ISS · (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal · in 2 records
- TAM · Tris(hydroxyethyl)aminomethane · in 2 records
- TBE · Tazobactam intermediate · in 2 records
- TSL · Trans-enamine intermediate of sulbactam · in 2 records
- NXL · (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide · in 1 record
Elsewhere
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