UniProt A0A0M3KL26
CFTR inhibitory factor (A0A0M3KL26)
CFTR inhibitory factor (UniProt A0A0M3KL26): 37 experimental structures on GenesisL1, 17 ligands bound, 160 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A0M3KL26
- Protein
- CFTR inhibitory factor
- Experimental structures
- 37
- Predicted models
- 0
- Ligands
- 17
- Pockets
- 160 · 17 records with a druggable one
Structures
37 records of A0A0M3KL26 in the MolNFT archive: 37 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5HK9 | Crystal structure of the CFTR inhibitory factor Cif bound to a urea inhibitor | x-ray diffraction | A, B, C, D | 64O | 10 (best 0.79) |
| 5HK9 | Crystal structure of the cftr inhibitory factor cif bound to a urea inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 5HKA | Crystal structure of the cftr inhibitory factor cif bound to an amide inhibitor | x-ray diffraction | A, B, C, D | — | — |
| 5HKB | Crystal structure of the cftr inhibitory factor cif bound to the inhibitor KB2115 | x-ray diffraction | A, B, C, D | — | — |
| 5JYC | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | A, B, C, D | EET | 8 (best 0.79) |
| 5JYC | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | — | — |
| 5TND | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | C, D, A, B | 40O, 3ZQ | — |
| 5TNE | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | 7F6 | — |
| 5TNF | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | A, B, C, D | 7HW | 9 (best 0.79) |
| 5TNF | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | 7HW | — |
| 5TNG | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | A, B, C, D | 7LE | 9 (best 0.80) |
| 5TNG | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | 7LE | — |
| 5TNH | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | C, D, A, B | 7MS | 9 (best 0.78) |
| 5TNH | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | C, D, A, B | 7MS | — |
| 5TNI | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | FEH | — |
| 5TNJ | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | A, B, C, D | AVH, 8MD, BVH, DVH | 8 (best 0.79) |
| 5TNJ | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | AVH, 8MD, BVH, DVH | — |
| 5TNK | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | A, B, C, D | 7F2 | 7 (best 0.83) |
| 5TNK | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | 7F2 | — |
| 5TNL | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | A, B, C, D | 7FB | 7 (best 0.79) |
| 5TNL | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | 7FB | — |
| 5TNM | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | A, B, C, D | 7F2 | 8 (best 0.81) |
| 5TNM | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | 7F2 | — |
| 5TNN | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | A, B, C, D | 7F2 | 11 (best 0.80) |
| 5TNN | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | 7F2 | — |
| 5TNP | Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted… | x-ray diffraction | A, B, C, D | FEH | 8 (best 0.80) |
| 5TNP | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | A, B, C, D | FEH | — |
| 5TNQ | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | C, D, A, B | FEH | — |
| 5TNR | Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the adducted… | x-ray diffraction | C, D, A, B | 7EZ | — |
| 5TNS | Crystal structure of the D129S mutant of the CFTR inhibitory factor Cif containing… | x-ray diffraction | A, B, C, D | 7EX | 9 (best 0.80) |
| 5TNS | Crystal structure of the D129S mutant of the cftr inhibitory factor cif containing… | x-ray diffraction | A, B, C, D | 7EX | — |
| 8EE2 | Crystal Structure of Nanobody VHH219 Bound to Its Antigen PA14 Cif | x-ray diffraction | A, B, E, F, I, J | — | 17 (best 0.88) |
| 8ELN | Crystal Structure of Nanobody VHH222 Bound to Its Antigen PA14 Cif | x-ray diffraction | A, B, E, F, I, J | — | 12 (best 0.87) |
| 8EVD | Crystal Structure of Nanobody VHH101 Bound to Its Antigen PA14 Cif | x-ray diffraction | C, D, G, H, K, L | — | 19 (best 0.77) |
| 8F6U | Crystal Structure of Nanobody VHH113 Bound to Its Antigen PA14 Cif | x-ray diffraction | D, C | — | 6 (best 0.65) |
| 8F6V | Crystal Structure of Nanobody VHH108 Bound to Its Antigen PA14 Cif | x-ray diffraction | D, C | — | — |
| 8GJR | Crystal Structure of Nanobody VHH114 Bound to Its Antigen PA14 Cif | x-ray diffraction | C | — | 3 (best 0.72) |
Ligands
- 7F2 · (2R)-octane-1,2-diol · in 6 records
- FEH · (1R)-1-phenylethane-1,2-diol · in 4 records
- 7EX · (1R,6S)-7-oxabicyclo[4.1.0]heptane · in 2 records
- 7FB · (2R)-hexane-1,2-diol · in 2 records
- 7HW · (4Z,7Z,10Z,13Z,16Z,19R,20R)-19,20-dihydroxydocosa-4,7, 10,13,16-pentaenoic acid · in 2 records
- 7LE · (5Z,8Z,11Z,14R,15R,17Z)-14,15-dihydroxyicosa-5,8,11,17-tetraenoic acid · in 2 records
- 7MS · (5Z,8Z,11Z,14Z,17R,18R)-17,18-dihydroxyicosa-5,8,11,14-tetraenoic acid · in 2 records
- 8MD · (1S,2S,4S)-4-ethenylcyclohexane-1,2-diol · in 2 records
- AVH · (1R,2R,4R)-4-ethenylcyclohexane-1,2-diol · in 2 records
- BVH · (1R,2R,4S)-4-ethenylcyclohexane-1,2-diol · in 2 records
- DVH · (1S,2S,4R)-4-ethenylcyclohexane-1,2-diol · in 2 records
- 3ZQ · (1S,2S)-cyclohexane-1,2-diol · in 1 record
- 40O · (1R,2R)-cyclohexane-1,2-diol · in 1 record
- 64O · N-(4-{[4'-(carbamoylamino)-6-hydroxybiphenyl-3-yl]oxy}-3,5-dichlorophenyl)propanamide · in 1 record
- 7EZ · (4Z,7Z,10Z,13Z,16R,17R,19Z)-16,17-dihydroxydocosa-4,7, 10,13,19-pentaenoic acid · in 1 record
- 7F6 · (1R,2R)-1,2-diphenylethane-1,2-diol · in 1 record
- EET · (5~{Z},11~{Z},14~{R},15~{R})-14,15-bis(oxidanyl)icosa-5,8,11-trienoic acid · in 1 record
Elsewhere
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