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Ligand · 7LE

7LE · (5Z,8Z,11Z,14R,15R,17Z)-14,15-dihydroxyicosa-5,8,11,17-tetraenoic acid

7LE, (5Z,8Z,11Z,14R,15R,17Z)-14,15-dihydroxyicosa-5,8,11,17-tetraenoic acid (C20 H32 O4, 336.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
7LE
Formula
C20 H32 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

7LE in 2 structures; the first of them:

  • 5TNG · Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the… · 7LE A401 · binds PHE63, ASP129, ILE130, TRP133, GLN153, ALA154, PRO155, PHE164 and 16 more
  • 5TNG · Crystal structure of the E153Q mutant of the cftr inhibitory factor cif containing the… · 7LE A401 · binds PHE63, ASP129, GLN153, ALA154, PRO155, PHE164, PRO165, SER173 and 10 more

Residues it binds most

PHE 8, HIS 8, PRO 7, TRP 7, ALA 8, ASP 8, GLN 8, MET 8, TYR 8, VAL 8 (residue and the binding sites it lines).

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