UniProt A0A0G3KF30

Ribosomal RNA large subunit methyltransferase J (A0A0G3KF30)

Ribosomal RNA large subunit methyltransferase J (UniProt A0A0G3KF30), EC 2.1.1.266: 6 experimental structures on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: A0A0G3KF30
Protein: Ribosomal RNA large subunit methyltransferase J
EC: 2.1.1.266
Experimental structures: 6
Predicted models: 0
Ligands: 3
Pockets: 20 · 3 records with a druggable one

Structures

6 records of A0A0G3KF30 in the MolNFT archive: 6 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6QDX	Structure of E.coli RlmJ in complex with a bisubstrate analogue (BA4)	x-ray diffraction	A, B, C, D	HY8	13 (best 0.71)
6QDX	Structure of E.COLI rlmj in complex with a bisubstrate analogue (BA4)	x-ray diffraction	A, B, C, D	HY8	—
6QE0	Structure of E.coli RlmJ in complex with a bisubstrate analogue (BA2)	x-ray diffraction	A	HZ2	2 (best 0.62)
6QE0	Structure of E.COLI rlmj in complex with a bisubstrate analogue (BA2)	x-ray diffraction	A	HZ2	—
6QE5	Structure of E.coli RlmJ in complex with the natural cofactor product S-adenosyl-homocysteine (SAH)	x-ray diffraction	A, B	SAH	5 (best 0.72)
6QE5	Structure of E.COLI rlmj in complex with the natural cofactor product S-adenosyl-homocysteine (sah)	x-ray diffraction	A, B	—	—

Ligands

HY8 · (2~{S})-4-[[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[3-[[9-[(2~{S},3~{R},4~{S},5~{S})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]propyl]amino]-2-azanyl-butanoic acid · in 2 records
HZ2 · (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-[2-[[9-[(2~{R},3~{R},4~{S},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl]purin-6-yl]amino]ethyl]amino]-2-azanyl-butanoic acid · in 2 records
SAH · S-adenosyl-L-homocysteine · in 1 record

Elsewhere

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