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UniProt A0A0C5B080

DNA topoisomerase 2 (A0A0C5B080)

DNA topoisomerase 2 (UniProt A0A0C5B080), EC 5.6.2.2: 3 experimental structures on GenesisL1, 2 ligands bound, 55 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
A0A0C5B080
Protein
DNA topoisomerase 2
EC
5.6.2.2
Experimental structures
3
Predicted models
0
Ligands
2
Pockets
55 · 3 records with a druggable one

Structures

3 records of A0A0C5B080 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8YGEpP1192R-DNA-m-AMSA complex DNA binding/cleavage domainelectron microscopyA, BMG, ASW20 (best 0.83)
8YGGpP1192R-apo Closed stateelectron microscopyA, B—18 (best 0.80)
8YGHpP1192R-apo open stateelectron microscopyA, B—17 (best 0.81)

Ligands

  • ASW · N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide · in 1 record
  • MG · Magnesium ion · in 1 record

Elsewhere

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