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Ligand · ASW

ASW · N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide

ASW, N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide (C21 H19 N3 O3 S, 393.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
ASW
Formula
C21 H19 N3 O3 S
Class
ligand
Structures
4
PDB entries
4

Binding sites

ASW in 4 structures; the first of them:

  • 8J9X · Cryo-EM structure of the African swine fever virus topoisomerase 2 complexed with… · ASW D1301 · binds ASP416, LEU470, GLY471, GLY472, VAL473, ILE474, LYS503, VAL504 and 4 more
  • 8JEM · DltB tetramer in complex with inhibitor m-AMSA · ASW A501 · binds TYR128, SER165, TYR242, LEU246, ASP249, PHE250, TYR253, TRP285 and 7 more
  • 8YGE · pP1192R-DNA-m-AMSA complex DNA binding/cleavage domain · ASW A1202 · binds ALA437, GLU438, LEU470, GLY471, GLY472, VAL473, ILE548, MET756 and 5 more
  • 8YO7 · structure of phage T6 topoisomerase II central domain bound with DNA and m-AMSA · ASW E101 · binds ASN78, ARG438, GLY439, LYS456, GLU457, DT13, DA14, DA10 and 1 more

Residues it binds most

TYR 4, TRP 4, GLY 6, DA 4, DT 4, HIS 4, PHE 4, LEU 7, LYS 6, VAL 4 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • DGA · Diacyl glycerol
  • PGT · (1S)-2-{[{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate
  • LMT · Dodecyl-beta-D-maltoside

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