UniProt A0A0C4DFX6
NPC1-like intracellular cholesterol transporter 1 (A0A0C4DFX6)
NPC1-like intracellular cholesterol transporter 1 (UniProt A0A0C4DFX6): 6 experimental structures on GenesisL1, 4 ligands bound, 24 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A0C4DFX6
- Protein
- NPC1-like intracellular cholesterol transporter 1
- Experimental structures
- 6
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 24 · 3 records with a druggable one
Structures
6 records of A0A0C4DFX6 in the MolNFT archive: 6 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DF8 | full length hNPC1L1-Apo | electron microscopy | A | NAG, CLR | 8 (best 0.88) |
| 7DF8 | Full length HNPC1L1-apo | electron microscopy | A | NAG, CLR | — |
| 7DFW | Cryo_EM structure of delta N-NPC1L1-CLR | electron microscopy | A | NAG, P5S, CLR | 8 (best 0.88) |
| 7DFW | CRYO_EM structure of delta N-NPC1L1-clr | electron microscopy | A | NAG, CLR | — |
| 7DFZ | Cryo_EM structure of delta N-NPC1L1-EZE | electron microscopy | A | NAG, H56, CLR | 8 (best 0.89) |
| 7DFZ | CRYO_EM structure of delta N-NPC1L1-eze | electron microscopy | A | NAG, H56, CLR | — |
Ligands
- CLR · Cholesterol · in 6 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 6 records
- H56 · (3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl) azetidin-2-one · in 2 records
- P5S · O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy) propyl]oxy}(hydroxy)phosphoryl]-L-serine · in 1 record
Elsewhere
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