UniProt A0A0A1E3Q0
DNA topoisomerase 2 (A0A0A1E3Q0)
DNA topoisomerase 2 (UniProt A0A0A1E3Q0): 11 experimental structures on GenesisL1, 4 ligands bound, 178 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A0A1E3Q0
- Protein
- DNA topoisomerase 2
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 178 · 11 records with a druggable one
Structures
11 records of A0A0A1E3Q0 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8J87 | Asfv topoisomerase 2 - apo conformer Ia | electron microscopy | A, B | — | 19 (best 0.83) |
| 8J88 | Asfv topoisomerase 2 - apo conformer Ib | electron microscopy | A, B | — | 16 (best 0.80) |
| 8J89 | Cryo-EM structure of Asfv topoisomerase 2 - apo conformer IIa | electron microscopy | A, B | — | 20 (best 0.79) |
| 8J8A | Cryo-EM structure of Asfv topoisomerase 2 - apo conformer IIb | electron microscopy | A, B | — | 18 (best 0.80) |
| 8J8B | Cryo-EM structure of Asfv topoisomerase 2 - apo conformer IIIa | electron microscopy | A, B | — | 19 (best 0.80) |
| 8J8C | Cryo-EM structure of Asfv topoisomerase 2 - apo conformer IIIb | electron microscopy | A, B | — | 20 (best 0.80) |
| 8J9V | Cryo-EM structure of the African swine fever virus topoisomerase 2 complexed with Cut02aDNA and… | electron microscopy | A, B | MG, EVP | 20 (best 0.80) |
| 8J9W | Cryo-EM structure of the African swine fever virus topoisomerase 2 complexed with Cut02bDNA and… | electron microscopy | A, B | MG, EVP | 20 (best 0.81) |
| 8J9X | Cryo-EM structure of the African swine fever virus topoisomerase 2 complexed with Cut02aDNA and… | electron microscopy | A, B | MG, ASW | 20 (best 0.85) |
| 8JA1 | ASFV Topoisomerase ATPase domain in complex with AMP-PNP and Mg2+ (oxidized form) | x-ray diffraction | A | MG, ANP | 3 (best 0.75) |
| 8JA2 | ASFV Topoisomerase ATPase domain in complex with AMP-PNP and Mg2+ | x-ray diffraction | A | MG, ANP | 3 (best 0.75) |
Ligands
- MG · Magnesium ion · in 5 records
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
- EVP · (5s,5ar,8ar,9r)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5A,6,8,8A,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside · in 2 records
- ASW · N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide · in 1 record
Elsewhere
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