UniProt A0A045KE74
Histidine N-alpha-methyltransferase (A0A045KE74)
Histidine N-alpha-methyltransferase (UniProt A0A045KE74), EC 2.1.1.44: 12 experimental structures on GenesisL1, 7 ligands bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A045KE74
- Protein
- Histidine N-alpha-methyltransferase
- EC
- 2.1.1.44
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 14 · 5 records with a druggable one
Structures
12 records of A0A045KE74 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7SCF | M. tb EgtD in complex with HD2 | x-ray diffraction | A, B | 8YI, PO4 | 4 (best 0.77) |
| 7SCF | M. tb egtd in complex with HD2 | x-ray diffraction | A, B | 8YI, PO4 | — |
| 7SEW | M. tb EgtD in complex with HD6 | x-ray diffraction | A | A1I | 1 (best 0.76) |
| 7SEW | M. tb egtd in complex with HD6 | x-ray diffraction | A | A1I | — |
| 7SEX | M. tb EgtD in complex with TGX221 | x-ray diffraction | A | 93I | — |
| 7SEX | M. tb egtd in complex with TGX221 | x-ray diffraction | A | 93I | — |
| 7SEY | M. tb EgtD in complex with SGH | x-ray diffraction | A | 92W | 1 (best 0.75) |
| 7SEY | M. tb egtd in complex with sgh | x-ray diffraction | A | 92W | — |
| 7SF4 | M. tb EgtD in complex with imatinib | x-ray diffraction | A, B | XDK | 4 (best 0.78) |
| 7SF4 | M. tb egtd in complex with imatinib | x-ray diffraction | A, B | XDK | — |
| 7SF5 | M. tb EgtD in complex with HD3 | x-ray diffraction | A, B | 95I | 4 (best 0.78) |
| 7SF5 | M. tb egtd in complex with HD3 | x-ray diffraction | A, B | 95I | — |
Ligands
- 8YI · (2S)-3-(1H-imidazol-5-yl)-2-(1H-pyrrol-1-yl)propanoic acid · in 2 records
- 92W · 2-amino-1-[(3S)-3-methyl-4-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepan-1-yl]ethan-1-one · in 2 records
- 93I · 7-methyl-2-morpholin-4-yl-9-[(1~{R})-1-phenylazanylethyl]-3~{H}-pyrido[1,2-a]pyrimidin-4-one · in 2 records
- 95I · N-(benzylcarbamothioyl)-L-histidine · in 2 records
- A1I · N-(cyclopent-3-ene-1-carbonyl)-L-histidine · in 2 records
- PO4 · Phosphate ion · in 2 records
- XDK · 2-amino-4-pyridyl-pyrimidine · in 2 records
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.