UniProt A0A045HD00
RNA polymerase sigma factor SigA (A0A045HD00)
RNA polymerase sigma factor SigA (UniProt A0A045HD00): 9 experimental structures on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- A0A045HD00
- Protein
- RNA polymerase sigma factor SigA
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 15 · 4 records with a druggable one
Structures
9 records of A0A045HD00 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6BZO | Mtb RNAP Holo/RbpA/Fidaxomicin/upstream fork DNA | electron microscopy | F | FI8 | 3 (best 0.85) |
| 6BZO | Mtb rnap HOLO/RBPA/FIDAXOMICIN/UPSTREAM fork DNA | electron microscopy | F | FI8 | — |
| 6C04 | Mtb RNAP Holo/RbpA/double fork DNA -closed clamp | electron microscopy | F | — | — |
| 6C04 | Mtb rnap HOLO/RBPA/DOUBLE fork DNA -closed clamp | electron microscopy | F | — | — |
| 6C05 | Mycobacterium tuberculosis RNAP Holo/RbpA in relaxed state | electron microscopy | F | — | 4 (best 0.86) |
| 6C05 | Mycobacterium tuberculosis rnap HOLO/RBPA in relaxed state | electron microscopy | F | — | — |
| 6C06 | Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin | electron microscopy | F | FI8 | 4 (best 0.88) |
| 6C06 | Mycobacterium tuberculosis rnap HOLO/RBPA/FIDAXOMICIN | electron microscopy | F | FI8 | — |
| 7U22 | Mycobacterium tuberculosis RNA polymerase sigma A holoenzyme open promoter complex containing UMN-7 | x-ray diffraction | F | KYO | 4 (best 0.79) |
Ligands
- FI8 · Fidaxomicin · in 4 records
- KYO · (9S,14S,15R,16S,17R,18R,19R,20S,21S,25R)-5,6,18,20-tetrahydroxy-14-methoxy-7,9,15,17,19,21,25-heptamethyl-1'-(2-methylpropyl)-10,26-dioxo-1,3,9,10-tetrahydrospiro[9,4-(epoxypentadecanoimino)furo[2',3':7,8]naphtho[1,2-d]imidazole-2,4'-piperidin]-16-yl benzoate · in 1 record
Elsewhere
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