GL1X · GenesisL1 explorer

Ligand · ZLV

ZLV · (3s,18s,20ar)-18-(6,6-dihydroxyoctyl)-1,5,6,7,8,18,19, 20A-octahydro-4H-14,17-epiminoazeto[1,2-G][1,7,10, 13]benzoxatriazacycloheptadecin-20(2H)-one

ZLV, (3s,18s,20ar)-18-(6,6-dihydroxyoctyl)-1,5,6,7,8,18,19, 20A-octahydro-4H-14,17-epiminoazeto[1,2-G][1,7,10, 13]benzoxatriazacycloheptadecin-20(2H)-one (C27 H40 N4 O4, 484.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1…

Component
ZLV
Formula
C27 H40 N4 O4
Class
ligand
Structures
1
PDB entries
1

Binding sites

ZLV in 1 structure; the first of them:

  • 7MOS · Structure of HDAC2 in complex with a macrocyclic inhibitor (compound 4) · ZLV A412 · binds GLY28, PRO30, MET31, GLU99, ASP100, HIS141, HIS142, GLY150 and 10 more

Residues it binds most

GLY 3, ASP 3, HIS 3, PHE 3, GLU 3, LEU 3, MET 3, PRO 3, TYR 3, CYS 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • PEG · Di(hydroxyethyl)ether

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