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Ligand · ZIY

ZIY · plitidepsin

ZIY, plitidepsin (C57 H87 N7 O15, 1110.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
ZIY
Formula
C57 H87 N7 O15
Class
ligand
Structures
2
PDB entries
2

Binding sites

ZIY in 2 structures; the first of them:

  • 8G5Z · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) · ZIY EF502 · binds LEU138, TYR141, THR142, LYS146, TYR177, LYS180, ILE181, GLY182 and 15 more
  • 8G60 · mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) · ZIY EF502 · binds LEU138, TYR141, THR142, LYS180, ILE181, GLY182, GLN343, ILE345 and 12 more

Residues it binds most

ARG 2, ILE 2, GLY 2, LEU 2, VAL 2, LYS 2, TYR 2, ALA 2, ASP 2, GLN 2 (residue and the binding sites it lines).

Found with

  • 3H3 · 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione
  • ANM · Anisomycin
  • GSP · 5'-guanosine-diphosphate-monothiophosphate
  • MET · Methionine
  • PHE · Phenylalanine
  • PUT · 1,4-diaminobutane
  • SPD · Spermidine
  • K · Potassium ion
  • MG · Magnesium ion
  • ZN · Zinc ion

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