Ligand · 3H3

3H3 · 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione

3H3, 4-{(2R,5S,6E)-2-hydroxy-5-methyl-7-[(2R,3S,4E,6Z,10E)-3-methyl-12-oxooxacyclododeca-4,6,10-trien-2-yl]-4-oxooct-6-en-1-yl}piperidine-2,6-dione (C26 H35 N O6, 457.6 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (5…

Component: 3H3
Formula: C26 H35 N O6
Class: ligand
Structures: 5
PDB entries: 5

Binding sites

3H3 in 5 structures; the first of them:

8G5Y · mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) · 3H3 L55523 · binds G91, C92, U4340, C4341, C4342, OMG4370, G4371, MLZ53 and 4 more
8G5Z · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) · 3H3 L55119 · binds G91, C92, U4340, C4341, C4342, OMG4370, G4371, MLZ53 and 4 more
8G60 · mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) · 3H3 L55117 · binds G91, C92, U4340, C4341, C4342, OMG4370, G4371, MLZ53 and 3 more
8G61 · mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) · 3H3 L55310 · binds G91, C92, U4340, C4341, C4342, OMG4370, G4371, A4379 and 5 more
8GLP · mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus… · 3H3 L55102 · binds G91, C92, U4340, C4341, C4342, OMG4370, G4371, MLZ53 and 4 more

Residues it binds most

C 5, G 5, ILE 5, MLZ 5, OMG 5, PHE 5, PRO 5, U 5, LYS 4, A 1 (residue and the binding sites it lines).

Found with

ANM · Anisomycin
MET · Methionine
PUT · 1,4-diaminobutane
SPD · Spermidine
K · Potassium ion
MG · Magnesium ion
ZN · Zinc ion
GSP · 5'-guanosine-diphosphate-monothiophosphate
PHE · Phenylalanine
ZIY · plitidepsin
TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

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