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Ligand · Z76

Z76 · N-[(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-{(2R)-4-[(3-methylphenyl)sulfonyl]piperazin-2-yl}ethyl]-3-{[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]carbonyl}-5-methylbenzamide

Z76, N-[(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-{(2R)-4-[(3-methylphenyl)sulfonyl]piperazin-2-yl}ethyl]-3-{[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]carbonyl}-5-methylbenzamide (C35 H42 F2 N4 O6 S, 684.8 g/mol), in the MolNFT structures on…

Component
Z76
Formula
C35 H42 F2 N4 O6 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

Z76 in 2 structures; the first of them:

  • 3LPK · Structure of BACE Bound to SCH747123 · Z76 A456 · binds SER71, GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96 and 21 more
  • 3LPK · Structure of bace bound to SCH747123 · Z76 A456 · binds SER71, GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96 and 21 more

Residues it binds most

GLY 4, ILE 4, SER 4, THR 4, ARG 4, ASP 4, GLN 4, TYR 4, LYS 4, LEU 4 (residue and the binding sites it lines).

Found with

  • TLA · L(+)-tartaric acid

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