Ligand · Z75

Z75 · N'-[(1S,2S)-2-[(2R)-4-benzylpiperazin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide

Z75, N'-[(1S,2S)-2-[(2R)-4-benzylpiperazin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide (C35 H44 F2 N4 O3, 606.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component: Z75
Formula: C35 H44 F2 N4 O3
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

Z75 in 2 structures; the first of them:

3LPJ · Structure of BACE Bound to SCH743641 · Z75 A456 · binds SER71, GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96 and 19 more
3LPJ · Structure of bace bound to SCH743641 · Z75 A456 · binds SER71, GLY72, GLN73, GLY74, LEU91, ASP93, GLY95, SER96 and 19 more

Residues it binds most

GLY 4, ILE 4, THR 4, ASP 4, GLN 4, SER 4, TYR 4, LYS 4, ARG 4, LEU 4 (residue and the binding sites it lines).

Found with

TLA · L(+)-tartaric acid

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