GL1X · GenesisL1 explorer

Ligand · Z5D

Z5D · (2E)-2-{2-[4-([1,1'-biphenyl]-4-yl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid

Z5D, (2E)-2-{2-[4-([1,1'-biphenyl]-4-yl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid (C24 H18 N4 O4 S, 458.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
Z5D
Formula
C24 H18 N4 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

Z5D in 2 structures; the first of them:

  • 7MEU · A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of… · Z5D A1001 · binds LEU45, PHE66, PHE72, LEU75, TYR76, ILE79, GLN80, LEU81 and 11 more
  • 7MEU · A biphenyl inhibitor of EIF4E targeting an internal binding site enables the design of… · Z5D A1001 · binds LEU45, PHE66, PHE72, LEU75, TYR76, ILE79, GLN80, LEU81 and 11 more

Residues it binds most

LEU 2, ARG 2, PHE 2, SER 2, TYR 2, ASN 2, ASP 2, GLN 2, ILE 2, TRP 2 (residue and the binding sites it lines).

Found with

  • MGP · 7-methyl-guanosine-5'-triphosphate

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.