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Ligand · Z34

Z34 · N-[2-[5-[amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro-6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylglycine

Z34, N-[2-[5-[amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro-6-[3-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylglycine (C25 H24 F2 N6 O5, 526.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records…

Component
Z34
Formula
C25 H24 F2 N6 O5
Class
ligand
Structures
2
PDB entries
1

Binding sites

Z34 in 2 structures; the first of them:

  • 1FJS · Crystal structure of the inhibitor zk-807834 (ci-1031) complexed with factor xa · Z34 A500 · binds LYS96, GLU97, THR98, TYR99, PHE174, ASP189, ALA190, CYS191 and 10 more
  • 1FJS · Crystal structure of the inhibitor zk-807834 (ci-1031) complexed with factor xa · Z34 A500 · binds LYS96, GLU97, THR98, TYR99, PHE174, ASP189, ALA190, CYS191 and 10 more

Residues it binds most

GLY 2, CYS 2, SER 2, ALA 2, ASP 2, GLN 2, GLU 2, ILE 2, LYS 2, PHE 2 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • CL · Chloride ion
  • GOL · Glycerol

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