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Ligand · YRB

YRB · (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone

YRB, (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-hep…

Component
YRB
Formula
C40 H71 N7 O9
Class
ligand
Structures
1
PDB entries
1

Binding sites

YRB in 1 structure; the first of them:

  • 8G6J · mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) · YRB EF503 · binds LEU138, TYR141, THR142, LYS146, LYS180, ILE181, GLN343, ILE345 and 13 more

Residues it binds most

ARG 1, ILE 1, GLY 1, LEU 1, LYS 1, PHE 1, VAL 1, ALA 1, ASP 1, GLN 1 (residue and the binding sites it lines).

Found with

  • 3HE · 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione
  • GSP · 5'-guanosine-diphosphate-monothiophosphate
  • HMT · (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine
  • MET · Methionine
  • PHE · Phenylalanine
  • PUT · 1,4-diaminobutane
  • SPD · Spermidine
  • K · Potassium ion
  • MG · Magnesium ion
  • ZN · Zinc ion

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