YKM · (1R,2S)-2-((S)-2-((((S)-1-(4,4-difluorocyclohexyl) ethoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic acid

Binding sites

YKM in 2 structures; the first of them:

• 7LZU · Structure of SARS-CoV-2 3CL protease in complex with inhibitor 12b · YKM A401 · binds HIS41, MET49, TYR54, PHE140, LEU141, ASN142, GLY143, SER144 and 12 more
• 7LZU · Structure of SARS-cov-2 3CL protease in complex with inhibitor 12B · YKM A401 · binds HIS41, MET49, TYR54, PHE140, LEU141, ASN142, GLY143, SER144 and 12 more

Residues it binds most

HIS 4, MET 4, LEU 4, ALA 4, ARG 4, ASN 4, ASP 4, CYS 4, GLN 4, GLU 4 (residue and the binding sites it lines).

Found with

• YKP · (1S,2S)-2-((S)-2-((((S)-1-(4,4-difluorocyclohexyl) ethoxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-((S)-2-oxopyrrolidin-3-yl)propane-1-sulfonic acid
• PG4 · Tetraethylene glycol