GL1X · GenesisL1 explorer

Ligand · YDA

YDA · 1-~{tert}-butyl-~{N}-[(5~{R})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide

YDA, 1-~{tert}-butyl-~{N}-[(5~{R})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide (C28 H34 N10 O2, 542.6 g/mol), in the MolNFT structures on GenesisL1…

Component
YDA
Formula
C28 H34 N10 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

YDA in 2 structures; the first of them:

  • 7LTZ · Bruton's tyrosine kinase in complex with compound 51 · YDA A701 · binds LEU408, GLY409, THR410, GLY411, GLN412, PHE413, VAL416, ALA428 and 16 more
  • 7LTZ · BRUTON'S tyrosine kinase in complex with compound 51 · YDA A701 · binds LEU408, GLY409, THR410, GLY411, GLN412, PHE413, VAL416, ALA428 and 16 more

Residues it binds most

GLY 2, LEU 2, ALA 2, ASP 2, SER 2, THR 2, TYR 2, VAL 2, ASN 2, GLN 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion
  • DTT · 2,3-dihydroxy-1,4-dithiobutane

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.