GL1X · GenesisL1 explorer

Ligand · WFS

WFS · (2r,3r,3as,6s,6ar)-6-[(2-amino-3-bromoquinolin-7-yl) oxy]-2-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl) hexahydro-3AH-cyclopenta[b]furan-3,3A-diol

WFS, (2r,3r,3as,6s,6ar)-6-[(2-amino-3-bromoquinolin-7-yl) oxy]-2-(4-methyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl) hexahydro-3AH-cyclopenta[b]furan-3,3A-diol (C23 H22 Br N5 O4, 512.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2…

Component
WFS
Formula
C23 H22 Br N5 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

WFS in 2 structures; the first of them:

  • 7KIC · PRMT5:MEP50 Complexed with 5,5-Bicyclic Inhibitor Compound 34 · WFS A706 · binds LEU312, PRO314, LEU315, LEU319, TYR324, PHE327, LYS333, TYR334 and 17 more
  • 7KIC · PRMT5:MEP50 complexed with 5,5-bicyclic inhibitor compound 34 · WFS A706 · binds PRO314, LEU315, LEU319, TYR324, PHE327, LYS333, GLY365, GLY367 and 15 more

Residues it binds most

LEU 2, GLU 2, GLY 2, LYS 2, SER 2, TYR 2, ARG 2, ASN 2, ASP 2, CYS 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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