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Ligand · WFR

WFR · propan-2-yl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-ethynyl-3-hydroxy-4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name)

WFR, propan-2-yl (2S)-2-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-ethynyl-3-hydroxy-4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate (non-preferred name) (C24 H30 N3 O9 P, 535.5 g/mol), in the…

Component
WFR
Formula
C24 H30 N3 O9 P
Class
ligand
Structures
2
PDB entries
2

Binding sites

WFR in 2 structures; the first of them:

  • 8E57 · Rabbit L-type voltage-gated calcium channel Cav1.1 in the presence of Amiodarone and 100… · WFR A1903 · binds MET291, PHE323, LEU326, LEU330, ASN649, LEU652, LEU653, PHE1013 and 8 more
  • 8E58 · Rabbit L-type voltage-gated calcium channel Cav1.1 in the presence of Amiodarone and 1 mM… · WFR A1903 · binds MET291, SER322, PHE323, LEU326, LEU330, ASN649, LEU653, LEU657 and 10 more

Residues it binds most

LEU 2, ALA 2, PHE 2, ASN 2, ILE 2, MET 2, VAL 2, SER 1, THR 1 (residue and the binding sites it lines).

Found with

  • BBI · (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
  • CA · Calcium ion
  • BMA · beta-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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