Ligand · VO7

VO7 · N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-5-{[4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl) propanamide

VO7, N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-5-{[4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl) propanamide (C27 H31 N7 O2, 485.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component: VO7
Formula: C27 H31 N7 O2
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

VO7 in 2 structures; the first of them:

7JXL · EGFR kinase (T790M/V948R) in complex with AZ5104 · VO7 D1101 · binds LEU718, GLY719, SER720, VAL726, ALA743, LYS745, MET790, GLN791 and 12 more
7JXL · EGFR kinase (T790M/V948R) in complex with AZ5104 · VO7 D1101 · binds LEU718, GLY719, SER720, VAL726, ALA743, MET790, GLN791, LEU792 and 9 more

Residues it binds most

LEU 8, ASP 8, MET 8, GLY 8, ALA 8, CYS 8, GLN 8, LYS 6, VAL 8, ARG 6 (residue and the binding sites it lines).

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