GL1X · GenesisL1 explorer

Ligand · VCD

VCD · 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole

VCD, 4-{4-[(3R)-3-methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (C21 H24 N4 O3 S, 412.5 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its…

Component
VCD
Formula
C21 H24 N4 O3 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

VCD in 4 structures; the first of them:

  • 7JJG · Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ATR kinase… · VCD A1701 · binds TRP1526, PRO1527, PHE1528, HIS1530, PRO1531, VAL1532, ASN1533, PHE1536 and 5 more
  • 7K27 · Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ATR… · VCD A1705 · binds TRP1526, PRO1527, PHE1528, HIS1530, PRO1531, VAL1532, ASN1533, PHE1536 and 5 more
  • 7JJG · Crystal structure of the second bromodomain (BD2) of human TAF1 bound to atr kinase… · VCD A1701 · binds TRP1526, PRO1527, PHE1528, HIS1530, PRO1531, VAL1532, ASN1533, PHE1536 and 4 more
  • 7K27 · Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to atr… · VCD A1705 · binds TRP1526, PRO1527, PHE1528, HIS1530, PRO1531, VAL1532, ASN1533, PHE1536 and 4 more

Residues it binds most

TYR 4, ASN 4, PHE 4, PRO 4, VAL 4, HIS 4, TRP 4 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • GOL · Glycerol
  • DMS · Dimethyl sulfoxide

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.