GL1X · GenesisL1 explorer

Ligand · VAT

VAT · 4-(2-azaspiro[3.4]octan-2-ylmethyl)-~{N}-[[(3~{R})-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide

VAT, 4-(2-azaspiro[3.4]octan-2-ylmethyl)-~{N}-[[(3~{R})-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide (C32 H40 N6 O2, 540.7 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
VAT
Formula
C32 H40 N6 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

VAT in 2 structures; the first of them:

  • 7OEF · Crystal structure of the human METTL3-METTL14 complex with compound UOZ038 · VAT A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, GLY407, THR408 and 12 more
  • 7OEF · Crystal structure of the human METTL3-METTL14 complex with compound UOZ038 · VAT A601 · binds CYS376, ASP377, ILE378, ARG379, ASP395, PRO396, GLY407, THR408 and 12 more

Residues it binds most

GLY 2, ARG 2, ASP 2, TRP 2, ASN 2, CYS 2, GLN 2, GLU 2, ILE 2, LEU 2 (residue and the binding sites it lines).

Found with

  • ACT · Acetate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.