GL1X · GenesisL1 explorer

Ligand · V88

V88 · 7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine

V88, 7-[3-(1,3-dihydroisoindol-2-yl)propoxy]-2N-[2-(dimethylamino)ethyl]-6-methoxy-4N-(1-propan-2-ylpiperidin-4-yl)quinazoline-2,4-diamine (C32 H47 N7 O2, 561.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
V88
Formula
C32 H47 N7 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

V88 in 2 structures; the first of them:

  • 7OCB · Crystal structure of Spindlin1 in complex with the inhibitor XY49-92B · V88 B301 · binds ASP95, HIS139, PHE141, TRP151, TYR170, TYR177, TYR179, ASP183 and 3 more
  • 7OCB · Crystal structure of SPINDLIN1 in complex with the inhibitor XY49-92B · V88 B301 · binds ASP95, HIS139, PHE141, TRP151, TYR170, TYR177, TYR179, ASP183 and 3 more

Residues it binds most

ASP 2, TYR 2, GLU 2, HIS 2, PHE 2, TRP 2 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • GLY · Glycine

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.